Systems Biology

Faculty of the Committee on Higher Degrees in Systems Biology

Cross-Listed Courses for Undergraduates and Graduates

Primarily for Graduates

Systems Biology 201. Biology of Animals: genetics, genomics, development and evolution
Catalog Number: 5148
Angela DePace (Medical School), Marc W. Kirschner (Medical School), and Sean G. Megason (Medical School)
Half course (spring term). Tu., Th., 2–3:30. EXAM GROUP: 16, 17
A paper-based discussion course focusing on genetics, genomics and systems biology approaches to the development, physiology and evolution of animals. Students will gain practice in critically evaluating data from genetics and genomics experiments, presenting the conclusions of a paper, and leading discussions on the impact of the work. We will also discuss areas where quantitative techniques have not yet been successful, and ask why not. At the end of the course, students will develop and present proposals for how to bring quantitative approaches to bear on specific biological questions.

[Systems Biology 202. Synthetic Biology] - (New Course)
Catalog Number: 30087
Pamela A. Silver (Medical School) and Jack Szostak (Medical School)
Half course (spring term). Hours to be arranged.
This course will cover the design and synthesis of new genetic circuits, construction of novel genomes and the chemical basis for building self-replicating systems.
Note: Expected to be given in 2010–11. Weekly lectures with discussion sections and outside speakers

Systems Biology 203. Fundamentals of Quantitative and Systems Biology - (New Course)
Catalog Number: 83523
Peter K. Sorger (Medical School) and Timothy J. Mitchison (Medical School)
Half course (fall term). M., W., F., 10:30–12. EXAM GROUP: 3, 4
Cell tissue biology from molecular, dynamical systems and information theoretic perspectives. Approaches to modeling biological pathways, collecting quantitative data and deriving mechanistic insight will be presented through weekly lectures, workshops and literature analysis.

Cross-Listed Courses Primarily for Graduates

Graduate Courses of Reading and Research

[*Systems Biology 301. Special Topics in Systems Biology]
Catalog Number: 8834
Instructor to be determined
Half course (fall term). Hours to be arranged.
An exploration of new directions for the field of systems biology. We will identify major unsolved questions in biology and discuss possible new approaches to these questions offered by systems biology.
Note: Expected to be given in 2010–11.

*Systems Biology 350. Systems Biology Research
Catalog Number: 8370
Pamela A. Silver (Medical School) 1595 and members of the Committee
Upper level Systems Biology students register for this course when they permanently join a lab. Students should register under the supervising PI.

*Systems Biology 399. Introduction to Systems Biology: Rotations
Catalog Number: 5863
Pamela A. Silver (Medical School) 1595
Half course (fall term; repeated spring term). Hours to be arranged.
The course will introduce the research areas of faculty performing research in systems biology. Intended for Systems Biology lab rotations.

Cross-Listed Graduate Courses of Reading and Research