Stem Cell and Regenerative Biology
Faculty of the Department of Stem Cell and Regenerative Biology (FAS, HMS)
William J. Anderson, Lecturer on Stem Cell & Regenerative Biology
Paola Arlotta, Assistant Professor of Stem Cell and Regenerative Biology, Assistant Professor of Surgery (Medical School)
Chad A. Cowan, Assistant Professor of Stem Cell and Regenerative Biology, Assistant Professor of Medicine (Medical School)
Kevin C. Eggan, Assistant Professor of Stem Cell and Regenerative Biology (Co-Head Tutor)
Konrad Hochedlinger, Assistant Professor of Stem Cell and Regenerative Biology, Assistant Professor of Medicine (Medical School)
Alexander Meissner, Assistant Professor of Stem Cell and Regenerative Biology
Lee L. Rubin, Senior Lecturer on Stem Cell and Regenerative Biology
Amy J. Wagers, Assistant Professor of Stem Cell and Regenerative Biology
Other Faculty Offering Instruction in Stem Cell and Regenerative Biology
Douglas A. Melton, Thomas Dudley Cabot Professor of the Natural Sciences, Harvard College Professor (Co-Chair, Co-Head Tutor)
David T. Scadden, Gerald and Darlene Jordan Professor of Medicine (Medical School) (Co-Chair)
Kenneth R. Chien, Charles Addison & Elizabeth Ann Sanders Professor of Medicine (Medical School)
George Q. Daley, Associate Professor of Biological Chemistry and Molecular Pharmacology (Medical School)
D. Gary Gilliland, Professor of Medicine (Medical School)
Jeffrey D. Macklis, Professor of Surgery and Neurology (Medical School)
Andrew P. McMahon, Frank B. Baird, Jr. Professor of Science (on leave 2008-09)
Leonard I. Zon, Grousbeck Professor of Pediatrics (Medical School)
For Undergraduate and Graduates
SCRB 125 (formerly MCB 125). Cloning and Regeneration
Catalog Number: 5481
Chad A. Cowan (Medical School) and Konrad Hochedlinger (Medical School)
Half course (spring term). M., W., 1–2:30. EXAM GROUP: 6, 7
This course will focus on the biology of stem cells, understanding the role stem cells play in normal development, how they give rise to differentiated cells and the role of pluripotency genes in stem cell self-renewal, reprogramming and cancer.
Prerequisite: LS1a, LS1b, MCB 52, or MCB 54, or permission of the instructor. MCB 118 is an ideal preparation.
SCRB 165. Directed Differentiation of Stem Cells - (New Course)
Catalog Number: 9605 Enrollment: Limited to 10.
Lee L. Rubin and Chad A. Cowan (Medical School)
Half course (spring term). F., 1–4; W., at 3. EXAM GROUP: 6, 7, 8
This practical laboratory course will investigate the fundamental biology of human embryonic stem cells and their remarkable capacity to differentiate into all cells of the body. The underlying developmental pathways that guide embryonic stem cell development into these differentiated cell types will be explored. A chemical biology approach will also be used to probe properties of normal and disease model cells derived from embryonic stem cells.
Prerequisite: LS1a or permission of instructor.
SCRB 167. What does Human Disease Teach Us About Mammalian Biology? - (New Course)
Catalog Number: 9556 Enrollment: Limited to 10. For advanced students only, seniors and qualified juniors.
George Q. Daley (Medical School), Kenneth R. Chien (Medical School), D. Gary Gilliland (Medical School), David T. Scadden (Medical School), and Leonard I. Zon (Medical School)
Half course (spring term). Hours to be arranged.
Stem cells are the basis for tissue maintenance and repair, thus, are essential elements of normal organ and tissue physiology. Stem cells are also targets for disease processes and through transplantation are important therapeutic agents. This course will allow advanced undergraduates to explore how stem cells and tissue regeneration impact human disease pathogenesis and how stem cells might be exploited to advance new therapies for disease.
Note: Two hour clinical: Thursday at Children’s Hospital Boston7th Floor Karp Building, Conference Rm. One hour discussion section: day and time TBD.
Prerequisite: LS1a, LS1b, MCB 52, or MCB 54.
SCRB 190. Understanding Aging: Degeneration, Regeneration, and the Scientific Search for the Fountain of Youth - (New Course)
Catalog Number: 1207
Amy J. Wagers and Lee L. Rubin
Half course (fall term). Tu., Th., 10–11:30. EXAM GROUP: 12, 13
This lecture and discussion course will explore the fundamental molecular and cellular mechanisms that govern organismal aging and contemporary strategies to delay or reverse this process.
Prerequisite: LS1a, LS1b, or MCB 54.
Cross-listed Courses
[*Chemistry 185 (formerly *Chemistry 285). Molecular Pathophysiology and Pharmacology of Human Disease]
[Chemistry 192. Principles of Drug Discovery and Development]
Government 1093. Ethics, Biotechnology, and the Future of Human Nature
Life Sciences 60 (formerly MCB 60). Ethics, Biotechnology, and the Future of Human Nature
[*MCB 118. From Egg to Embryo to Organ]
[MCB 141. Molecular and Developmental Neurobiology]
MCB 150. Developmental Genetics and Genomics
Primarily for Graduates
Cross-listed Courses
MCB 234. Cellular Metabolism and Human Disease