MCB 54. Cell Biology
Catalog Number: 0801
Robert A. Lue and Alexander F. Schier
Half course (spring term). M., W., F., at 10, and one laboratory/discussion session weekly. EXAM GROUP: 3
An integrated introduction to the structure, function, and interactions of cells. Topics covered include: membrane structure and transport, receptors and channels, protein targeting, cytoskeleton, cell cycle, signal transduction, cell migration, cell growth and death, cell adhesion, cell polarity, embryogenesis, organogenesis, and stem cells.
Note: Laboratory and discussion sessions focus on problem solving and evaluation of data. A series of linked laboratory exercises provides exposure to several techniques commonly used in cell biology and developmental biology. This course, when taken for a letter grade, meets the General Education requirement for Science of Living Systems or the Core area requirement for Science B.
Prerequisite: Life and Physical Sciences A or Life Sciences 1a; Life Sciences 1b recommended.
[MCB 55. Logic and Mechanism of Metabolic Pathways] - (New Course)
Catalog Number: 13144
Nicole J. Francis and Vladimir Denic
Half course (spring term). Hours to be arranged.
This course introduces the major metabolic pathways with an emphasis on how enzymes are organized into multi-component molecular machines that drive the flow of molecules through pathways, and on the regulation of these pathways. The focus will be on the logic of pathways and cycles-the "rules of the game"-rather than an exhaustive catalog of metabolism. Both historical and modern studies will be covered, including insights from metabolomics and other global methodologies.
Note: Expected to be given in 2010–11.
MCB 56. Physical Properties of Macromolecules
Catalog Number: 5424
Rachelle Gaudet
Half course (spring term). M., W., F., at 9, and a weekly section to be arranged. EXAM GROUP: 2
The course aims to develop fundamental concepts of physical chemistry as they apply to macromolecules, including protein and nucleic acid structure, thermodynamics and kinetics, ligand interactions and chemical equilibria. The course will also emphasize how these concepts are used in studies of the structure and function of biological molecules.
Prerequisite: Life and Physical Sciences A or Life Sciences 1a; MCB 52; Chemistry 17/27 or Chemistry 20/30 (Chemistry 27 may be concurrent); Math 1b. Physics at the level of PS 2/3 is recommended but not required.
MCB 80. Neurobiology of Behavior
Catalog Number: 6052
Joshua R. Sanes and Jeff W. Lichtman
Half course (fall term). Tu., Th., 1-2:30, and a 90-minute section to be arranged. EXAM GROUP: 15, 16
An introduction to the ways in which the brain controls mental activities. The course covers the cells and signals that process and transmit information, and the ways in which neurons form circuits that change with experience. Topics include the neurobiology of perception, learning, memory, language, emotion, and mental illness.
Note: This course, when taken for a letter grade, meets the General Education requirement for Science of Living Systems or the Core area requirement for Science B. The course is open to students with little formal training in biology.
*MCB 99. Laboratory Research for Honors Thesis
Catalog Number: 2987
A. Thomas Torello and members of the Department
Full course (indivisible). Hours to be arranged.
For honors candidates writing a thesis in Molecular and Cellular Biology. Indivisible for students enrolling in the fall term. Students intending to enroll in the fall are required to submit a written proposal to the instructor. Students may enter the course at midyear only with the permission of the instructor. The thesis proposal must be approved by the instructor and Head Tutor prior to enrolling in MCB 99.
Note: Ordinarily may not be taken as a fifth course.
MCB 110. Introduction to Quantitative Tools for Cell Biology - (New Course)
Catalog Number: 58465
Philippe Cluzel
Half course (spring term). M., W., 1:30–3. EXAM GROUP: 6, 7
This class will introduce students to the physical and mathematical tools that have become essential to analyze and understand data in cell biology. We will review concepts initially developed in physics in order to discuss real examples borrowed from classic experiments in biology. Topics to be covered: Noise, stochastic processes, single molecules, single-cell biology, robustness and evolvability of intracellular networks, modularity in biology, chaos, cell-to-cell variability, cell fate variability, cell-to-cell communication.
Prerequisite: Knowledge of elementary statistical mechanics is helpful, but not necessary.
MCB 111. Mathematics in Biology
Catalog Number: 6444
Sharad Ramanathan
Half course (spring term). M., W., 10–11:30. EXAM GROUP: 3, 4
Develops the mathematics needed for quantitative understanding of biological phenomena including data analysis, simple models, and framing quantitative questions. Topics include probability, transforms and linear algebra, and dynamical systems, each motivated by current biological research.
Note: Intended for biology students who do not have strong quantitative backgrounds.
Prerequisite: Mathematics 19 or higher.
MCB 115. Cellular Basis of Neuronal Function
Catalog Number: 8703
Venkatesh N. Murthy
Half course (fall term). W., F., 2–3:30. EXAM GROUP: 7, 8
Cellular processes involved in the function of neurons will be explored, with emphasis on biophysical and cell biological approaches. Topics include excitable membranes, intracellular membrane trafficking, cytoskeletal dynamics, synaptic transmission, dendritic integration, and synaptic plasticity.
*MCB 118. From Egg to Embryo to Organ
Catalog Number: 0749
Andrew P. McMahon
Half course (fall term). M., W., 2:30–4. EXAM GROUP: 7, 8
We will explore the molecular and cellular developmental mechanisms that regulate the progressive elaboration of a functional adult body plan through the study of vertebrate and invertebrate experimental model systems.
Prerequisite: Life and Physcial Sciences A or Life Sciences 1a (or equivalent); Life Sciences 1b or MCB 54 recommended.
*MCB 122. The Biology of Cell Division and Cancer
Catalog Number: 4353
Raymond L. Erikson
Half course (fall term). M., W., 1–2:30. EXAM GROUP: 6, 7
The molecular and cellular interfaces between normal cells and cancer cells will be covered in lectures and readings from the original literature. Topics will include conversion of extracellular signals to intracellular signals, protein kinase networks, mitosis, cell death, oncogenes, and suppressor genes.
Prerequisite: Recommended: MCB 52 and MCB 54.
*MCB 129. Molecular Genetics of Neural Development and Behavior
Catalog Number: 8956 Enrollment: Limited to 20.
Samuel M. Kunes
Half course (fall term). M., W., 10–11:30. EXAM GROUP: 3, 4
A lecture and discussion course on the development of the nervous system and the relationship between genes and behavior. Topics include neural differentiation and cell identity, cell birth and death, axon guidance and synaptic specificity, behavioral genetics. Emphasis on critical evaluation of readings from the primary literature, experimental design and scientific writing.
Prerequisite: Permission of the instructor.
MCB 131. Computational Neuroscience
Catalog Number: 9868
Haim I. Sompolinsky (Hebrew University)
Half course (spring term). Tu., Th., 1–2:30. EXAM GROUP: 15, 16
Follows trends in modern brain theory, focusing on local neuronal circuits as basic computational modules. Explores the relation between network architecture, dynamics, and function. Introduces tools from information theory, statistical inference, and the learning theory for the study of experience-dependent neural codes. Specific topics: computational principles of early sensory systems; adaptation and gain control in vision, dynamics of recurrent networks; feature selectivity in cortical circuits; memory; learning and synaptic plasticity; noise and chaos in neuronal systems.
Prerequisite: Basic knowledge of multivariate calculus, differential equations, linear algebra, and elementary probability theory.
[MCB 141. Molecular and Developmental Neurobiology]
Catalog Number: 5205
Catherine Dulac
Half course (spring term). Hours to be arranged.
Molecular basis of sensory perception and formation of related neuronal networks during vertebrate development. Topics will include mechanisms of sensory discrimination at the level of receptor molecules and receptor cells, coding of sensory information by the brain, and establishment of appropriate connections in the developing brain. Molecular and genetic approaches to memory and behavior will be discussed.
Note: Expected to be given in 2010–11.
Prerequisite: MCB 52 and MCB 80.
*MCB 142. Major Advances in Classical and Molecular Genetics
Catalog Number: 7948 Enrollment: Limited to 20.
Matthew Meselson
Half course (fall term). Tu., Th., 2–3:30. EXAM GROUP: 16, 17
MCB 142 aims to develop an understanding of the conceptual development of classical and molecular genetics, starting with Mendel and Darwin. Course work includes critical reading of selected papers on the chrimosomal and molecular basis of heredity, student presentations, group discussion, and submission of written answers to problem sets. Participation in class discussion of readings is essential. A substantial essay on a mutually agreed topic is due at end of reading period.
Note: This course, when taken for a letter grade, meets the Core area requirement for Science B.
Prerequisite: Life Sciences 1b or equivalent and permission of the instructor.
*MCB 145 (formerly *Neurobiology 95hfb). Neurobiology of Perception and Decision Making
Catalog Number: 6972
Naoshige Uchida
Half course (fall term). Tu., Th., 10–11:30. EXAM GROUP: 12, 13
One of the current goals of neuroscience is to understand neuronal circuits underlying perception and behavior. Recent advances in neuroscience have allowed us to glimpse neuronal processes that link perception and decision making. How is sensory information procesed in the brain? How does an animal chose its action? How does an animal learn from ever-changing environments and adjust their behavior? The course will examine neurophysiological studies in perception and decision-making.
Prerequisite: MCB 80 and permission of the instructor.
*MCB 146 (formerly *Neurobiology 95c). Experience-Based Brain Development: Causes and Consequences
Catalog Number: 5390
Takao K. Hensch
Half course (spring term). Tu., Th., 2–3:30. EXAM GROUP: 16, 17
At no time in life does the surrounding environment so potently shape brain function as in infancy and early childhood. This course integrates molecular/cellular biology with systems neuroscience to explore biological mechanisms underlying critical periods in brain development. Understanding how neuronal circuits are sculpted by experience will motivate further consideration of the social impact on therapy, education, policy, and ethics.
Prerequisite: Life and Physical Sciences A or Life Sciences 1a, MCB 80, and permission of the instructor.
MCB 147. Brain Circuits - (New Course)
Catalog Number: 73572
Markus Meister
Half course (spring term). M., W., 1:30–3. EXAM GROUP: 6, 7
What functions arise when many thousands of neurons combine in a densely connected circuit? Though the operations of neural circuits lie at the very heart of brain science, our textbooks have little to say on the topic. This course explores what is known, and how we will learn more. The emphasis is on experimental science, but theory and computation play important roles in interpreting data and formalizing predictions.
Prerequisite: MCB 80 or equivalent; some recent math experience.
MCB 150. Developmental Genetics and Genomics
Catalog Number: 5703
Kevin C. Eggan
Half course (fall term). M., W., 4–5:30. EXAM GROUP: 9
The process by which genes, and traits they encode, are transmitted from one cell to another and one generation to the next will be explored. A conceptual foundation for genetic analysis will be established through studies of model organisms including yeast, C. elegans, Drosophila and mouse. Classical approaches and modern transgenic techniques will be explained and ultimately applied towards the understanding of human genetics. Primarily lecture based with some discussion of primary scientific literature.
Prerequisite: Life and Physical Sciences A or Life Sciences 1a (or equivalent), Life Sciences 1b (or equivalent), and MCB 52.
MCB 151. From the Gene to the Phenotype
Catalog Number: 5799
William M. Gelbart
Half course (spring term). Hours to be arranged.
This course will explore how the information encoded in our genomes leads to both the shared phenotypic characteristics of a species as well as individual variation. Both the classical literature and the current state of the art will be discussed.
Prerequisite: Life Sciences 1b, or permission of the instructor.
[MCB 152. Genetic Analysis]
Catalog Number: 6788
Craig P. Hunter
Half course (fall term). Hours to be arranged.
An advanced course focusing on genetic analysis of fundamental cellular and developmental processes in model organisms. An emphasis is placed on reading and understanding the primary literature through introductory lectures, class discussions, and short written assignments. Students will learn how to design and interpret genetic experiments in a variety of model organisms.
Note: Expected to be given in 2010–11.
Prerequisite: Life Sciences 1b, MCB 52, and MCB 54.
*MCB 155. Molecular Mechanisms of Gene Control
Catalog Number: 6230
Nicole J. Francis and Vladimir Denic
Half course (spring term). Tu., Th., 4–6. EXAM GROUP: 18
An advanced course on the control of gene regulation. Topics include: mechanisms of gene regulation at the level of transcription, chromatin structure, DNA methylation, RNA processing, mRNA localization, and protein synthesis and degradation. The course is taught through weekly lectures and readings from the current literature. Topics covered in lectures and the reading assignments are discussed in sections. Students are required to critically evaluate and discuss recent papers in sections. Two exams.
Prerequisite: MCB 52 and MCB 54 (or equivalent), and permission of instructor.
MCB 156. Structural Biology of the Flow of Information in the Cell
Catalog Number: 8543
David Jeruzalmi
Half course (spring term). Tu., Th., 2–3:30. EXAM GROUP: 16, 17
A journey that follows the path taken by an extra-cellular signal as it reaches a cell, traverses the plasma membrane, navigates the cytoplasm, and finally manifests its effect upon the genome. Through the reading and discussion of primary research literature, the course highlights how structural biology has helped develop a detailed picture of each step in the pathway. The interplay between cellular and network biology and structural biology is also emphasized.
Prerequisite: Introductory molecular and cellular biology (MCB 52 and MCB 54 or equivalent).
MCB 169. Molecular and Cellular Immunology
Catalog Number: 2518
Shiv S. Pillai (Medical School)
Half course (fall term). Tu., Th., 10-11:30, and a 90-minute section to be arranged. EXAM GROUP: 12, 13
The immune system is frontier at which molecular biology, cell biology, and genetics intersect with the pathogenesis of disease. The course examines in depth the cellular and molecular mechanisms involved in the development and function of the immune system and also analyzes the immunological basis of human disease including AIDS and other infectious diseases, autoimmune disorders, allergic disorders, primary immunodeficiency syndromes, transplantation, and cancer.
Prerequisite: Life and Physical Sciences A or Life Sciences 1a or equivalent. Genetics and cell biology strongly recommended.
[*MCB 173. Optical Imaging in the Biological Sciences]
Catalog Number: 3836
Jeff W. Lichtman
Half course (fall term). Hours to be arranged.
The optical microscope has undergone a radical transformation. Recent innovations in lasers, chemistry, molecular biology, detectors, computation and optics have propelled the microscope to the cutting edge of modern biology. These complex machines are now the tools of choice for revealing structure and function in biology. This course explores the principles and practice of the “new microscopy”. Topics include the nature of light, fluorescence, image restoration, confocal, 2-photon, structured illumination and other new techniques.
Note: Expected to be given in 2010–11.
Prerequisite: Permission of the instructor; MCB 80 recommended.
MCB 176. Biochemistry of Membranes
Catalog Number: 3186
Guido Guidotti
Half course (fall term). M., W., 2–4. EXAM GROUP: 7, 8
A course on the properties of biological membranes, essential elements for cell individuality, communication between cells, and energy transduction. Topics include: membrane structure; membrane protein synthesis, insertion in the bilayer and targeting; transporters, pumps and channels; electron transport, H+ gradients and ATP synthesis; membrane receptors, G proteins and signal transduction; membrane fusion.
Prerequisite: MCB 52 and MCB 54 are recommended but not required.
MCB 185. Molecular Pathophysiology and Pharmacology of Human Disease
Catalog Number: 1124
Vicki L. Sato and Gregory L. Verdine
Half course (spring term). Th., 2–5. EXAM GROUP: 16, 17, 18
This course will address both the molecular basis of human disease and the biological and chemical foundation of therapeutic intervention. The course will include lectures by prominent experts and analysis of the primary literature.
Note: May not be taken concurrently with Chemistry 185. May not be taken for credit if Chemistry 185 or Chemistry 285 have already been taken.
Prerequisite: Chemistry 20/30 or 17/27, MCB 52, or their equivalents.
MCB 186. Circadian Biology: From Cellular Oscillators to Sleep Regulation
Catalog Number: 2854
J. Woodland Hastings and Charles A. Czeisler (Medical School)
Half course (fall term). W., 2-5, and a weekly section to be arranged. EXAM GROUP: 7, 8, 9
Properties, mechanisms, and functional roles of circadian (daily) rhythms in organisms ranging from unicells to mammals. Cellular and molecular components, regulation of gene expression and physiological functions, genetic and biochemical analyses of circadian rhythms, and neurobiology of the mammalian circadian pacemaker. Mathematics and modeling of oscillatory systems and applications to circadian rhythms. Experimental studies of human rhythms, including the sleep-wake cycle and hormone rhythms, with applications to sleep disorders.
Prerequisite: Life Sciences 1b or equivalent, MCB 80 desirable.
MCB 188. Chromosomes
Catalog Number: 8561
Nancy Kleckner
Half course (spring term). Tu., Th., 2–4. EXAM GROUP: 16, 17
Chromosome morphogenesis in prokaryotic and eukaryotic organisms. Topics will include chromosome structure, interactions between chromosomes (sisters and homologs), DNA recombination and repair, topoisomerases, transposable elements and site-specific recombination, epigenetic inheritance. Genetic, cytological, and biochemical approaches will be integrated. Lecture, reading, and discussion of classical and current literature and consideration of future experimental directions.
Prerequisite: Life Sciences 1b or equivalent, MCB 52, and MCB 54.
[MCB 192. Principles of Drug Discovery and Development]
Catalog Number: 2188 Enrollment: Limited to 40.
Vicki L. Sato and Gregory L. Verdine
Half course (spring term). Hours to be arranged.
This interdisciplinary course will examine the process of drug discovery and development through disease-driven examples. Topics include: the efficacy/toxicity balance, the differences between drugs and inhibitors, the translation of cellular biochemistry to useful medicine.
Note: Expected to be given in 2010–11. May not be taken concurrently with Chemistry 192. May not be taken for credit if Chemistry 192 has already been taken.
Prerequisite: MCB 52 and one year of organic chemistry. MCB 54 is recommended.
[MCB 195. Foundations of Systems Biology and Biological Engineering]
Catalog Number: 9112
Instructor to be determined
Half course (spring term). Tu., Th., 10–11:30.
This course builds an understanding of design principles in biology. We will ask why biological circuits are built the way they are and answer using mathematical models. Topics: elementary circuits in biological networks, robustness, pattern-formation in embryos, error-correction, and evolutionary optimization.
Note: Expected to be given in 2010–11. Students from physics, engineering and other disciplines are also welcome.
Prerequisite: Life and Physical Sciences A or Life Sciences 1a, Life Sciences 1b and Mathematics 1a/1b and molecular cell biology at the level of MCB 52 and MCB 54. Familiarity with mathematics at the level of 19/20 is strongly recommended.
MCB 199. Statistical Thermodynamics and Quantitative Biology
Catalog Number: 9072
Howard C. Berg
Half course (spring term). M., W., F., at 11. EXAM GROUP: 4
Physical biology of the cell. Life at rest and in motion. Transformation of matter and energy. Elements of probability and statistics. The Boltzmann distribution. The random walk and diffusion. Applications in biomechanics and sensory physiology.
Prerequisite: Two terms of college calculus, a calculus-based physics course, and some exposure to molecular and cellular biology. Experience with statistics and differential equations not essential, but helpful.
[*MCB 208. Talking about Science]
Catalog Number: 3605 Enrollment: Limited to 30.
Jeff W. Lichtman and Michael E. Greenberg (Medical School)
Half course (spring term). Tu., 7–8:30 p.m.
Teaches advanced students how to give a good research talk while exposing them to seminal scientific discoveries. Emphasis will be on speaking style, lecture organization, and use of video projection tools.
Note: Expected to be given in 2010–11. In addition to lecture material from the instructor, students will present experiments from Nobel Prize-winning work. The presentations will be critiqued in class by the participants. Open to second year graduate students or by permission of the instructor.
[MCB 212. Topics in Biophysics]
Catalog Number: 3351
Howard C. Berg
Half course (spring term). Hours to be arranged.
Motility and sensory transduction; chemotaxis in bacteria; flagellar motility; prokaryotic and eukaryotic motor molecules.
Note: Expected to be given in 2010–11. Given in alternate years. A term paper and seminar are required.
MCB 225. Interesting Questions in Physical Biology
Catalog Number: 7646
Nancy Kleckner and David A. Weitz
Half course (fall term). Tu., Th., 1–2:30. EXAM GROUP: 15, 16
Physical biology can be defined as a discipline that seeks to understand biological processes through the lens of physics and engineering. Faculty and students will unite to review current research with the aim of identifying and pondering interesting emerging questions in this area.
Note: Intended primarily for first year graduate students in the EPB PhD track but available to other graduate students and advanced undergraduates as space permits.
MCB 234. Cellular Metabolism and Human Disease
Catalog Number: 0870
Thomas Michel (Medical School), Robert A. Lue and members of the Department
Half course (spring term). M., W., F., 9–10:30. EXAM GROUP: 2, 3
Cellular and organismal metabolism, with focus on interrelationships between key metabolic pathways and human disease states. Genetic and acquired metabolic diseases and functional consequences for specific organ systems. Lectures and conferences are integrated with clinical encounters with patients.
Note: Students may attend lectures in either Cambridge or Boston since they will be transmitted live from HMS to Harvard College and vice-versa; the inter-campus link will allow real-time interactions between students and faculty at each site. May not be taken concurrently with BCMP 234. May not be taken for credit if BCMP 234 has already been taken.
Prerequisite: Knowledge of introductory biochemistry, genetics, and cell biology required (MCB 52 and MCB 54 or equivalent); one year of organic chemistry.
MCB 235. Principles of Human Disease: Physiology and Pharmacology
Catalog Number: 9139
David E. Golan (Medical School), Julian L. Seifter (Medical School), David E. Sloane (Medical School), and Alain Viel
Half course (fall term). M., W., F., 9–10:30. EXAM GROUP: 2, 3
Principles of human physiology, pathophysiology and drug action–including mechanisms of organ function in health and disease and strategies for designing drug-based therapeutic interventions–discussed in lectures, critical readings, clinical case scenarios, and patient presentations.
Note: May not be taken concurrently with BCMP 235. May not be taken for credit if BCMP 235 has already been taken.
Prerequisite: Knowledge of introductory biochemistry, molecular biology, and cell biology required (MCB52 and MCB54 or equivalent); one year of organic chemistry.
MCB 254. Advanced Cell Biology
Catalog Number: 1622
Matthew Michael
Half course (spring term). M., W., 10–11:30. EXAM GROUP: 3, 4
This course covers advanced topics in modern cell biology. It is intended for graduate students and advanced undergraduates. The course is organized around important unanswered questions in cell biology. Examples include: what is the fate of the Golgi at mitosis; how do cells and tissues know how big they are? Each week a different question will be addressed through a combination of discussion of primary research papers and lectures.
MCB 268. Molecular Immunology: Seminar
Catalog Number: 2196 Enrollment: Limited to 16.
Jack L. Strominger
Half course (spring term). M., Th., 4–6. EXAM GROUP: 9, 18
One session each week is a lecture on the topics. At the second session four papers are read from the current literature, each presented by a student in 20-30 minutes. Course work: reading of papers, seminar presentations, and class participation.
Prerequisite: MCB 169 or permission of instructor required for undergraduates only.
MCB 291. Genetics, Genomics and Evolutionary Biology
Catalog Number: 2833
Cassandra G. Extavour and Elena M. Kramer
Half course (fall term). M., 9–10:30, W., 1–2:30. EXAM GROUP: 2, 3, 6, 7
This course covers the fundamentals of classical genetics, molecular genetics, macro- and microevolution, phylogenetics, and developmental evolution. The emphasis is on major concepts and terminology, reading landmark primary literature, and acquainting students with research techniques.
Note: Intended for graduate students in the Molecules, Cells and Organisms (MCO) Training Program.
*MCB 292. Cellular Biology, Neurobiology and Developmental Biology
Catalog Number: 4288 Enrollment: Limited to 20.
Craig P. Hunter and John E. Dowling
Half course (fall term). Tu., Th., 10–11:30. EXAM GROUP: 12, 13
The biology of the individual cell lies at the heart of multi-cellular phenomena such as development and neural function. This course will emphasize critical evaluation of the primary literature, experimental design and scientific writing.
Note: Intended for graduate students in the Molecules, Cells and Organisms (MCO) Training Program.
MCB 293. Physical, Chemical and Molecular Biology
Catalog Number: 2706
Andres Leschziner and Victoria M. D’Souza
Half course (fall term). Hours to be arranged.
This course will introduce basic principles in general, organic and physical chemistry, including kinetics and thermodynamics, as well as macromolecular structure. Concepts will be illustrated with examples taken from the visual system.
Note: Intended for graduate students in the Molecules, Cells and Organisms (MCO) Training Program.
*MCB 301. Synapse Formation
Catalog Number: 3935
Joshua R. Sanes 5094
*MCB 303. Mechanisms of Epigenetic Inheritance by Polycomb Group Proteins
Catalog Number: 3144
Nicole J. Francis 5227
*MCB 304. Experimental Biological Physics and Quantitative Cell Biology
Catalog Number: 5730
Daniel Joseph Needleman 6151
*MCB 305. Signaling Processing and Systems Biology
Catalog Number: 1443
Sharad Ramanathan 6015
*MCB 306. Biophysics and Physiology of Neurons
Catalog Number: 1695
Venkatesh N. Murthy 2424
*MCB 307. Developmental Genetics and Neurobiology
Catalog Number: 8554
Alexander F. Schier 5238
*MCB 308. Quantitative Analysis of Regulatory Networks
Catalog Number: 2226
Erin K. O’Shea 5239 (on leave 2009-10)
*MCB 311. Biochemistry of Epigenetics
Catalog Number: 6131
Nicole J. Francis 5227
*MCB 312. Military and Arms Control Applications of Biology and Chemistry
Catalog Number: 2063
Matthew Meselson 1319
*MCB 315. Structural Biology of Signaling and Transport Through Biological Membranes
Catalog Number: 9560
Rachelle Gaudet 4413
*MCB 316. Structural Biology of Retroviral Replication
Catalog Number: 8769
Victoria M. D’Souza 5584
*MCB 317. Structure and Function of the Biological Assemblies Involved in DNA Replication
Catalog Number: 6396
David Jeruzalmi 4528
*MCB 322. Genetics and Development
Catalog Number: 7290
Craig P. Hunter 2803
*MCB 326. Biochemical Virology
Catalog Number: 0243
Raymond L. Erikson 7506
*MCB 327. DNA Damage Induced Signal Transduction
Catalog Number: 8684
Matthew Michael 3825
*MCB 328. Neuronal Circuit Development
Catalog Number: 5728
Takao K. Hensch 5813
*MCB 329. Structural Biology of ATP-Dependent Chromatin Remodeling
Catalog Number: 6060
Andres Leschziner 5928
*MCB 330. Mechanisms of DNA Transport Across Membranes
Catalog Number: 7228
Briana Burton 6214
*MCB 331. Single-Cell Analysis of Transcriptional and Signaling Networks in Bacteria
Catalog Number: 4064
Philippe Cluzel 6215
*MCB 332. Mechanisms of Membrane-Based Cell Biological Processes
Catalog Number: 9806
Vladimir Denic 6216
*MCB 344. Molecular and Developmental Neurobiology
Catalog Number: 2292
Catherine Dulac 2801
*MCB 359. Chromosomes
Catalog Number: 6278
Nancy Kleckner 4697
*MCB 363. Invertebrate Development and Transcriptional Circuitry - (New Course)
Catalog Number: 15771
Susan Mango 6386
*MCB 364. Vertebrate Development
Catalog Number: 1396
Andrew P. McMahon 3312
*MCB 365. Neurobiology
Catalog Number: 8349
John E. Dowling 3545
*MCB 366. Synaptic Plasticity and Neuronal Networks
Catalog Number: 1085
Florian Engert 4290
*MCB 367. Structural Studies of Synapses
Catalog Number: 1850
Jeff W. Lichtman 5163
*MCB 368. Neural Circuits for Sensation and Behavior - (New Course)
Catalog Number: 30878
Naoshige Uchida 5745
*MCB 373. Cellular Biochemistry and Physiology
Catalog Number: 8053
J. Woodland Hastings 1311
*MCB 374. Developmental Neurobiology
Catalog Number: 6167
Samuel M. Kunes 3486
*MCB 377. Genetics and Development
Catalog Number: 5598
William M. Gelbart 4774
*MCB 378. Motile Behavior of Bacteria
Catalog Number: 5729
Howard C. Berg 1377
*MCB 381. Microbial Development
Catalog Number: 4994
Richard M. Losick 3561
*MCB 382. Molecular Immunology
Catalog Number: 5515
Jack L. Strominger 1193
*MCB 386. Molecular Evolution
Catalog Number: 0763
Matthew Meselson 1319
*MCB 390. Function of Neuronal Circuits
Catalog Number: 8883
Markus Meister 3007
*MCB 391. Biochemistry
Catalog Number: 4888
Guido Guidotti 1203
*MCB 395. Mechanisms of Gene Regulation
Catalog Number: 7697
Thomas Maniatis 7231
*MCB 396. Regulation of Mitosis
Catalog Number: 5706
Andrew W. Murray 3765 (on leave 2009-10)
*Microbiology 312. Acquired and Innate Immunity to Pneumococci - (New Course)
Catalog Number: 78191
Richard Malley 6461